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Download vMix Torrent For macThe olfactory bulb is the primary relay between the sense of smell and the cerebral cortex, where information is processed and where higher order functions of perception are performed. Its distinctive layered architecture, with exclusive functional states characteristic of the different layers, has served as a model for the study of other projection neurons and neural circuits in the brain. In the mature olfactory bulb, olfactory sensory neurons depolarize and fire action potentials upon odor stimulation. Before being amplified and processed in the glomeruli, these odor-evoked signals are transferred from the periphery by axon collaterals of these sensory neurons to the bulb’s mitral and tufted cells. The axon collaterals form synapses on the somata and proximal dendrites of the mitral and tufted cells. Electrophysiological studies indicate that the synapse formed by the axon collaterals is asymmetric, with inhibition coming from the axon terminal. As a result, action potentials in the mitral and tufted cells are dominated by incoming inhibition. This inhibition likely comes from olfactory sensory neurons which express the inhibitory neurotransmitter gamma- aminobutyric acid (GABA). The proposed studies will analyze the inhibitory synapses formed by the axon collaterals of mitral and tufted cells to elucidate how the inhibition from these synapses shapes mitral and tufted cell odor responses and mitigates stimulus-evoked activity in the olfactory bulb. The proposed experiments will address three Specific Aims: 1) To determine the GABAergic sources of inhibition that synapse on mitral and tufted cells; 2) To investigate the receptor subunits expressed by the mitral and tufted cells; and 3) To assess the interactions between glomerular inhibition and mitral and tufted cell odor responses. These studies will use immunohistochemical, electrophysiological and pharmacological approaches to address the mechanisms by which inhibitory synapses shape mitral and tufted cell odor responses. The proposed experiments will contribute to a better understanding of the role of inhibition in olfactory processing in the brain. Finally, these studies will address a brain

https://colab.research.google.com/drive/1ZZIStYyYMpiUv2cTN48eSYFokhcH5gxG
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This is a partial list of named minor planets in numerical order. It contains a total of 100 entries. Minor planets for which no article exist are displayed in and redirect to the list of minor planets (see ).

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