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pokemon hoenn rom hackcode, pokemon, pokemon pkm nintendo gamecube, pokemon qr code, pokemon gameboy, pokemon gameboy. Nintendo Zone Volume 6 ¿ Original: DL-DOL-G3TJ-JPN: Dairantou Smash Brothers DX. (The Legend of Zelda: The Wind Waker USA).a, 5-hydroxymethylcytosine (5-hmC), glycine (Gly) and N6-methyladenosine (m^6^A) are RNA modifications in mRNAs, respectively \[[@pone.0181883.ref016]\]. **(B)** The m^6^A RNA modification predominantly occurs in stop codons \[[@pone.0181883.ref011]\]. The m^6^A modification at the stop codons can prevent the termination translation at the stop codon \[[@pone.0181883.ref017]\]. **(C)** miR-BART20-5p can target the m^6^A modification at the stop codons and can facilitate the expression of the viral proteins.](pone.0181883.g003){#pone.0181883.g003}

In conclusion, using genome-wide m^6^A-IPseq, we identified that m^6^A can be globally regulated in the JS-PC-1 cells. The upregulation of m^6^A in *PA28γ* knockout cells may be due to the decrease in the m^6^A RNA methylation. Furthermore, the increase in the m^6^A modification can assist the function of miR-BART20-5p, which can target the m^6^A modification at the stop codons. This study may provide more insights into the regulation of m^6^A and the functional role of m^6^A in the viral infection.

Supporting information {#sec014}
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